Comparative efficacy of albendazole and three brands of mebendazole in the treatment of ascariasis and trichuriasis.

Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm.

The three main soil-transmitted helminth infections, ascariasis, trichuriasis, and hookworm, are common clinical disorders in man. The gastrointestinal tract of a child living in poverty in a less developed country is likely to be parasitised with at least one, and in many cases all three soil-transmitted helminths, with resultant impairments in physical, intellectual, and cognitive development...

Global deworming: moving past albendazole and mebendazole.

Since the 2001 adoption of the World Health Assembly (WHA) resolution calling for the global deworming of children affected by soil-transmitted helminth (STH) infections and schistosomiasis, the world’s public health leaders have gradually responded. Although we are still behind schedule in terms of the WHA’s original 2010 targets, WHO continues to report progress— in 2015, approximately 59% of...

In vivo effect of albendazole and mebendazole on hydatid cyst of mice

In current study, a few sheep cystic livers and lungs were obtained from Mashhad slaughter house and protoscolex were separated aseptically. Thirty 6-week-old Swiss mice were divided into 5 groups and two thousands of live protoscolices were inoculated intrapritoaneally in each mouse. In group 1 and 2 (prophylactic groups), mice were given 150 mg/kg of oral albendazole and mebendazole for 10 da...

The Efficacy of Albendazole Mebendazole Combination Against Echinococcus granulosus Protoscoleces (an in vitro evaluation)

A comparison of the efficacy of single doses of albendazole, ivermectin, and diethylcarbamazine alone or in combinations against Ascaris and Trichuris spp.

OBJECTIVE To determine the efficacy of single doses of albendazole, ivermectin and diethylcarbamazine, and of the combinations albendazole + ivermectin and albendazole + diethylcarbamazine against common intestinal helminthiases caused by Ascaris and Trichuris spp. METHODS In a randomized, placebo-controlled trial, infected children were randomly assigned to treatment with albendazole + place...